Everything about John Jacob Abel totally explained
John Jacob Abel (
May 19,
1857 –
May 26,
1938) was a significant
American biochemist and
pharmacologist.
Born near
Cleveland,
Ohio, he graduated with a Ph.D. 1883 from the
University of Michigan. In
1891 he founded and chaired the first department of pharmacology in the United States at the University of Michigan. In
1893, he went on to chair the pharmacology department at
Johns Hopkins University. In
1897, he was the second to isolate
epinephrine, also known as adrenaline (the first was
Napoleon Cybulski in 1895), although the extracts he produced have been shown to be mostly an inactive metabolite and the first pure extracts were produced by the japanese
Jokichi Takamine (1854-1922) who patented the formulation under the name
adrenalin. He later formulated the idea of the artificial
kidney and in
1914 he isolated
amino acids from the
blood.
He spent years unsuccessfully searching for the
pituitary hormone, unaware that he was in fact looking for several hormones. In
1926, he reported the isolation and
crystallization of
insulin, though this announcement was met with considerable scepticism and not generally accepted for many years.
Abel also co-founded the
Journal of Biological Chemistry with
Christian Archibald Herter in
1905 and the
Journal of Pharmacology and Experimental Therapeutics in
1909.
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